I suppose I should begin this post with an explanation of what exactly endometreosis is, in case anyone is unfamiliar with the condition.
Endometreosis “is an often painful disorder in which tissue similar to the tissue that normally lines the inside of your uterus — the endometrium — grows outside your uterus … with endometriosis, the endometrial-like tissue acts as endometrial tissue would — it thickens, breaks down and bleeds with each menstrual cycle. But because this tissue has no way to exit your body, it becomes trapped. When endometriosis involves the ovaries, cysts called endometriomas may form. Surrounding tissue can become irritated, eventually developing scar tissue and adhesions — abnormal bands of fibrous tissue that can cause pelvic tissues and organs to stick to each other,” says Mayo Clinic.
Now that we’re all informed of this condition, let’s delve into discussion regarding the use of THC to treat it.
“In January 2020, a research team led by Rafael Maldanado published a study investigating an unlikely endometriosis treatment option: THC. And while these experiments were done using mice, their findings were so significant that clinical tests on women are now being funded at the Gynecology Service of the Clinical Hospital of Barcelona,” the article continues.
The researchers involved with the study observed three things in the mice being tested; how THC impacts pain-related anxiety, how THC influenced pain-related memory deficiencies, and also how THC interferes with endometrial growths on the uterus, the article says.
“The results were surprising, even to the researchers. First, implants that mimic the pain caused by endometriosis were placed in the pelvises of a group of female mice. These implants are already known to cause growths on mice uteruses, just like endometriosis. The implanted group was found to be more anxious; specifically less willing to explore new spaces. They also had a harder time remembering and identifying objects than their pain-free counterparts.
“Out of the group of mice with endometriosis-mimicking pain implants, a portion were dosed with 2mg/kg THC for 28 days. The THC-treated mice were shown to be less anxious than their untreated counterparts, and their memory test results were no different than the control group of pain-free mice,” explains the article.
If this treatment proves to be successful, this will be a momentous achievement in the context of women’s health.